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KMID : 0604520140400010029
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Journal of the Society of Cosmetic Scientists of Korea
2014 Volume.40 No. 1 p.29 ~ p.36
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Comparative Study of Protocorm-like body and Multiple Shoots from Dendrobium Candidum on Biological Activities
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Park Chang-Min
Kwon Ju-Chan
Han Na-Kyeong
Joung Min-Seok
Paek Kee-Yoeup
Choi Jong-Wan
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Abstract
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Dendrobium candidum is one of the well-known orchid on traditional and rare medicinal herb in China. Weartificially cultured protocorm-like body and multiple shoots using the bioreactor culture system from Dendrobium candidumand experimented an efficacy as a cosmetic ingredient for skin care. Several studies previously have reported anti-tumor, wound healing and immunological function of Dendrobium candidum but other efficacies were not well known.In the present study, we investigated the cosmetic efficacy to know applicable value of protocorm-like body and multipleshoots cultured from Dendrobium candidum as a cosmetic ingredient. The biological activities of extracts from protocorm-like body, multiple shoots, aerial part and underground part of Dendrobium candidum were investigated. Resultswere found that extracts of protocorm-like body are superior to other extracts (underground part, aerial part and multipleshoots extracts) on anti-oxidant effect. Also, protocorm-like body extract contained the phenolic and flavonoid compoundsmore than aerial part, underground part and multiple shoots extracts. In addition, we investigated skin whiteningeffect related to whitening of skin. In tyrosinase activity and melanin synthesis assay, multiple shoots extract is superiorto other extracts (aerial part, underground part and protocorm-like body), on inhibitory effect of tyrosinase activity andmelanin synthesis respectively. These results indicate that the protocorm-like body and multiple shoots extracts cultured from Dendrobium candidum presents a new possibility of being applicable to skin improvement as a cosmetic ingredient.
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KEYWORD
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Dendrobium candidum, anti-oxidation, biological activity, protocorm-like body, multiple shoots
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